SMC4

 Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene.^[5][6][7] SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation.

SMC4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4U4P
Identifiers
Aliases	SMC4, CAP-C, CAPC, SMC-4, SMC4L1, hCAP-C, structural maintenance of chromosomes 4
External IDs	OMIM: 605575 MGI: 1917349 HomoloGene: 4015 GeneCards: SMC4
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q25.33 Start 160,399,274 bp[1] End 160,434,954 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 E1 Start 69,004,738 bp[2] End 69,034,623 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein heterodimerization activity • nucleotide binding • GO:0001948 protein binding • ATP binding • single-stranded DNA binding Cellular component • chromosome • cell nucleus • condensin complex • nucleoplasm • cytoplasm • cytosol • nuclear speck Biological process • mitotic sister chromatid segregation • meiotic chromosome segregation • cell division • cell cycle • kinetochore organization • mitotic chromosome condensation • meiotic chromosome condensation • chromosome condensation • chromosome organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10051	70099
Ensembl	ENSG00000113810	ENSMUSG00000034349
UniProt	Q9NTJ3	Q8CG47
RefSeq (mRNA)	NM_001002799 NM_001002800 NM_001288753 NM_005496	NM_133786 NM_001356976
RefSeq (protein)	NP_001002800 NP_001275682 NP_005487	NP_598547 NP_001343905
Location (UCSC)	Chr 3: 160.4 – 160.43 Mb	Chr 3: 69 – 69.03 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This article uses material from the Wikipedia article  Metasyntactic variable, which is released under the  Creative Commons Attribution-ShareAlike 3.0 Unported License.