NADPH oxidase 3 is an enzyme that in humans is encoded by the NOX3 gene.[5][6]
| NOX3 |
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| Identifiers |
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| Aliases | NOX3, GP91-3, MOX-2, NADPH oxidase 3 |
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| External IDs | OMIM: 607105 MGI: 2681162 HomoloGene: 49435 GeneCards: NOX3 |
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| Gene location (Human) |
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 | | Chr. | Chromosome 6 (human)[1] |
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| | Band | 6q25.3 | Start | 155,395,368 bp[1] |
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| End | 155,455,839 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 17 (mouse)[2] |
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| | Band | 17 A1|17 2.05 cM | Start | 3,635,240 bp[2] |
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| End | 3,696,261 bp[2] |
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| RNA expression pattern |
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 | | More reference expression data |
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| Gene ontology |
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| Molecular function | • oxidoreductase activity
• superoxide-generating NADPH oxidase activity
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| Cellular component | • cytoplasm
• integral component of membrane
• cell membrane
• NADPH oxidase complex
• extracellular exosome
• membrane
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| Biological process | • response to gravity
• temperature homeostasis
• detection of gravity
• otolith development
• oxidation-reduction process
• superoxide anion generation
• defense response
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| Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 6: 155.4 – 155.46 Mb | Chr 17: 3.64 – 3.7 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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FunctionEditNADPH oxidases, such as NOX3, are plasma membrane-associated enzymes found in many cell types. They catalyze the production of superoxide by a 1-electron reduction of oxygen, using NADPH as the electron donor.[supplied by OMIM][6]
