NLRP14

 NLRP14, short for NOD-like receptor family pyrin domain containing 14, is an intracellular protein of mammals associated with a role in spermatogenesis. It is also known as NALP14, NOD5, GC-LRR, Nalp-iota, PAN8, and CLR11.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.^[5] NLRP14 is found exclusively in the testes where it is expressed within spermatogonia, spermatocytes and spermatids.^[6]

NLRP14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4N1J, 4N1K, 4N1L
Identifiers
Aliases	NLRP14, CLR11.2, GC-LRR, NALP14, NOD5, PAN8, NLR family, pyrin domain containing 14, NLR family pyrin domain containing 14
External IDs	OMIM: 609665 MGI: 1924108 HomoloGene: 18531 GeneCards: NLRP14
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 7,020,446 bp[1] End 7,071,308 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E3 Start 107,166,990 bp[2] End 107,198,102 bp[2]
Gene ontology Molecular function • ATP binding • nucleotide binding Cellular component • cytoplasm Biological process • cell differentiation • multicellular organism development • spermatogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	338323	76858
Ensembl	ENSG00000158077	ENSMUSG00000016626
UniProt	Q86W24	Q6B966
RefSeq (mRNA)	NM_176822	NM_001002894
RefSeq (protein)	NP_789792	NP_001002894
Location (UCSC)	Chr 11: 7.02 – 7.07 Mb	Chr 7: 107.17 – 107.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This article uses material from the Wikipedia article  Metasyntactic variable, which is released under the  Creative Commons Attribution-ShareAlike 3.0 Unported License.