Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene.[5][6]
| AQP7 |
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|
| Identifiers |
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| Aliases | AQP7, AQP7L, AQP9, AQPap, GLYCQTL, aquaporin 7 |
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| External IDs | OMIM: 602974 MGI: 1314647 HomoloGene: 48000 GeneCards: AQP7 |
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| Gene location (Human) |
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 | | Chr. | Chromosome 9 (human)[1] |
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| | Band | 9p13.3 | Start | 33,383,179 bp[1] |
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| End | 33,402,682 bp[1] |
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|
| Gene location (Mouse) |
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 | | Chr. | Chromosome 4 (mouse)[2] |
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| | Band | 4|4 A5 | Start | 41,033,074 bp[2] |
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| End | 41,048,139 bp[2] |
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|
| RNA expression pattern |
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 | | More reference expression data |
|
| Gene ontology |
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| Molecular function | • glycerol channel activity
• water channel activity
• channel activity
• urea transmembrane transporter activity
|
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| Cellular component | • cytoplasm
• integral component of membrane
• cell membrane
• integral component of plasma membrane
• membrane
• intercellular junction
• lipid droplet
• cell cortex
• cytoplasmic vesicle membrane
• cytoplasmic vesicle
|
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| Biological process | • water transport
• excretion
• glycerol transport
• generation of precursor metabolites and energy
• transmembrane transport
• urea transmembrane transport
|
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| Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | NM_001170
NM_001318156
NM_001318157
NM_001318158
NM_001376191
|
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NM_001376192
NM_001376193 |
| |
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| RefSeq (protein) | NP_001161
NP_001305085
NP_001305086
NP_001305087
NP_001363120
|
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NP_001363121
NP_001363122 |
| NP_031499
NP_001365567
NP_001365568
NP_001365569
NP_001365570
|
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NP_001365571 |
|
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| Location (UCSC) | Chr 9: 33.38 – 33.4 Mb | Chr 4: 41.03 – 41.05 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
|
Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in thermoregulation in the form of perspiration and sperm function.[6]
