Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene.[5]
| AQP6 |
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| Available structures |
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| PDB | Ortholog search: PDBe RCSB |
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| Identifiers |
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| Aliases | AQP6, AQP2L, KID, aquaporin 6 |
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| External IDs | OMIM: 601383 MGI: 1341204 HomoloGene: 20399 GeneCards: AQP6 |
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| Gene location (Human) |
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 | | Chr. | Chromosome 12 (human)[1] |
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| | Band | 12q13.12 | Start | 49,967,194 bp[1] |
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| End | 49,977,139 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 15 (mouse)[2] |
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| | Band | 15 F1|15 56.13 cM | Start | 99,601,400 bp[2] |
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| End | 99,605,477 bp[2] |
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| Gene ontology |
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| Molecular function | • nitrate transmembrane transporter activity
• water channel activity
• channel activity
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| Cellular component | • integral component of membrane
• cytoplasmic vesicle
• integral component of plasma membrane
• apical plasma membrane
• membrane
• cytoplasmic vesicle membrane
• cell membrane
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| Biological process | • nitrate transport
• excretion
• odontogenesis
• ion transmembrane transport
• transmembrane transport
• water transport
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| Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 12: 49.97 – 49.98 Mb | Chr 15: 99.6 – 99.61 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13.[5]
