Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the APOC4 gene.[5][6]
| APOC4 |
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| Identifiers |
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| Aliases | APOC4, APO-CIV, APOC-IV, apolipoprotein C4 |
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| External IDs | OMIM: 600745 MGI: 87878 HomoloGene: 1245 GeneCards: APOC4 |
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| Gene location (Human) |
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 | | Chr. | Chromosome 19 (human)[1] |
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| | Band | 19q13.32 | Start | 44,942,237 bp[1] |
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| End | 44,945,496 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 7 (mouse)[2] |
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| | Band | 7 A3|7 9.94 cM | Start | 19,678,083 bp[2] |
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| End | 19,681,479 bp[2] |
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| Gene ontology |
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| Molecular function | • lipid transporter activity
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| Cellular component | • high-density lipoprotein particle
• extracellular region
• very-low-density lipoprotein particle
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| Biological process | • lipid transport
• positive regulation of sequestering of triglyceride
• triglyceride homeostasis
• lipid metabolism
• very-low-density lipoprotein particle assembly
• very-low-density lipoprotein particle clearance
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| Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 19: 44.94 – 44.95 Mb | Chr 7: 19.68 – 19.68 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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FunctionEditAPOC4 is a member of the apolipoprotein C gene family. It is expressed in the liver and has a predicted protein structure characteristic of the other genes in this family. APOC4 is a 3.3-kb gene consisting of 3 exons and 2 introns; it is located 0.5 kb 5' to the APOC2 gene.[5]
